ESTIMATION OF HEMOGLOBIN LEVELS IN PATIENTS WITH ORAL POTENTIALLY MALIGNANT DISORDERS- A CASE CONTROL STUDY
Undergraduate student, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai,Tamilnadu
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Dr. Sangavi .R,
Senior lecturer, Department of oral medicine, Radiology and Special care dentistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences,
Saveetha University, Chennai 77, Tamil Nadu, India
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Dr. Adimulapu Hima Sandeep
Associate Professor, Department of conservative and endodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha university,
Chennai – 600077, Tamil Nadu, India, Email Id: firstname.lastname@example.org
A precancerous lesion is a morphologically altered tissue in which oral cancer is more likely to occur than in its apparently normal counterpart.A precancerous condition is a generalized state associated with a significantly increased risk of cancer.The most prevalent oral mucosal conditions with a high rate of malignant transformation are oral leukoplakia, oral submucous fibrosis, and oral erythroplakia. Clinically, there are six different subtypes of oral lichen planus, including papular, reticular, plaque-like, atrophic, erosive, and bullous types. This condition is one of the potentially cancerous conditions. In comparison to other subtypes, atrophic and erosive subtypes have a higher probability of malignant transformation. Despite numerous etiological studies, the exact cause of almost all of these diseases is still unknown.
MATERIALS AND METHODS
The hemoglobin levels of patients in the outpatient ward of Oral Medicine and Radiology department, Saveetha Dental College are assessed in this study. The test group contains patients who have oral premalignant lesions such as Oral Lichen Planus, Oral Leukoplakia and Oral Submucous Fibrosis which is 50 patients.The control group contains patients who does not have any systemic disorders which is 50 patients.The results are tabulated and cross verified for any biases. The results are then entered into SPSS software for data analysis.
RESULTS AND DISCUSSION
The results obtained from the study are presented as statistical barcharts.The comparison between the hemoglobin levels of the control group and the test group are evaluated.From the given data,the hemoglobin levels of the control group is significantly lower than the control group.
From the above results,the data was analyzed and concluded that the patients who have oral premalignant lesions have significantly lower hemoglobin levels than the patients with no specific lesions.Thus they can be used as a prognostic tool in the diagnosis patients who are at risk of premalignant lesions