Abstract:-“Chromone” is regarded as a significant unit of chemical because a large number of its variants with side chain at various locations form a diverse range of heterocyclic naturally occurring oxygen compounds called as flavonoid. Two thiadiazole derivatives were synthesized using different reagents and procedures and then were evaluated to check their antibacterial; and antifungal activity. Both the compounds were synthesized and characterized using IR. The compounds were found to possess antibacterial and antifungal activity to a good extent. They were effective against two out of three bacterial strains that we used to test. Thiadiazole derivative can be effective and potent candidates for antimicrobial activity and can be further used to treat microbial infections.

Keywords: Alkyl and aryl, Chromone, Flavones, Heterocyclic compounds, Thiadiazols , flavonoids .